diff --git a/packages/babel-preset-env/src/targets-parser.js b/packages/babel-preset-env/src/targets-parser.js
index 445e0fbdee..f054d9d746 100644
--- a/packages/babel-preset-env/src/targets-parser.js
+++ b/packages/babel-preset-env/src/targets-parser.js
@@ -174,7 +174,7 @@ const getTargets = (targets: Object = {}, options: Object = {}): Targets => {
 
   // Parse browsers target via browserslist
   const browsersquery = validateBrowsers(targets.browsers);
-  if (!options.ignoreBrowserslistConfig) {
+  if (targets.esmodules || !options.ignoreBrowserslistConfig) {
     browserslist.defaults = objectToBrowserslist(targets);
 
     const browsers = browserslist(browsersquery, { path: options.configPath });
diff --git a/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/browserslist b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/browserslist
new file mode 100644
index 0000000000..d0ae78fe6a
--- /dev/null
+++ b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/browserslist
@@ -0,0 +1 @@
+chrome 55
diff --git a/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/input.mjs b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/input.mjs
new file mode 100644
index 0000000000..f9e8d5a956
--- /dev/null
+++ b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/input.mjs
@@ -0,0 +1 @@
+const a = new Map();
diff --git a/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/options.json b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/options.json
new file mode 100644
index 0000000000..7792da9ef4
--- /dev/null
+++ b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/options.json
@@ -0,0 +1,12 @@
+{
+  "presets": [
+    ["../../../../lib", {
+      "configPath": "../fixtures/preset-options-add-used-built-ins/browserslist-config-ignore",
+      "modules": false,
+      "ignoreBrowserslistConfig": true,
+      "targets": { "esmodules": true },
+      "useBuiltIns": "usage",
+      "debug": true
+    }]
+  ]
+}
diff --git a/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/output.mjs b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/output.mjs
new file mode 100644
index 0000000000..ecbade1e6b
--- /dev/null
+++ b/packages/babel-preset-env/test/fixtures/preset-options-add-used-built-ins/browserslist-config-ignore/output.mjs
@@ -0,0 +1,2 @@
+import "core-js/modules/web.dom.iterable";
+const a = new Map();